Anti-GGH antibody [R38-1R-2] (STJA0035619)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human Gamma glutamyl hydrolase
General Information
| Short Description | Rabbit monoclonal anti-GGH for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R38-1R-2 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000 |
| Formulation | Liquid in PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | GGH |
| Gene ID | 8836 |
| Uniprot ID | GGH_HUMAN |
| Immunogen | A synthesized peptide derived from human Gamma glutamyl hydrolase |
Additional Info
| Function | Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha-glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates. |
| Protein Name | Gamma-Glutamyl HydrolaseConjugaseGhGamma-Glu-X Carboxypeptidase |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | SecretedExtracellular SpaceLysosomeMelanosomeWhile Its Intracellular Location Is Primarily The LysosomeMost Of The Enzyme Activity Is SecretedIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
| Alternative Antibody Names | Anti-Gamma-Glutamyl Hydrolase antibodyAnti-Conjugase antibodyAnti-Gh antibodyAnti-Gamma-Glu-X Carboxypeptidase antibodyAnti-GGH antibody |
Information sourced from Uniprot.org