Anti-GGCX antibody (400-450) {FITC} (STJ501153)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationFITC
IsotypeIgG
ImmunogenSynthetic peptide taken within amino acid region 400-450 on human GGCX protein.
STJ501153-100
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General Information

Short DescriptionRabbit polyclonal antibody anti-GGCX (400-450) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
ApplicationsELISA/IHC/IP/WB
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationFITC
Concentration0.55-0.75 ยตg/ยตl
PurificationAffinity Purified
Dilution RangeWB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
IP: 1:150
IHC: 1:50-1:100
FormulationContains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide).
Storage InstructionStore at-20ยฐC for long term storage. Avoid freeze-thaw cycles.

Target Information

Gene SymbolGGCX
Gene ID2677
Uniprot IDVKGC_HUMAN
ImmunogenSynthetic peptide taken within amino acid region 400-450 on human GGCX protein.
Immunogen Region400-450

Additional Info

Function Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide. Catalyzes gamma-carboxylation of various proteins, such as blood coagulation factors (F2, F7, F9 and F10), osteocalcin (BGLAP) or matrix Gla protein (MGP).
Protein Name Vitamin K-Dependent Gamma-Carboxylase
Gamma-Glutamyl Carboxylase
Peptidyl-Glutamate 4-Carboxylase
Vitamin K Gamma Glutamyl Carboxylase
Database Links Reactome: R-HSA-159740
Reactome: R-HSA-9673240
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Vitamin K-Dependent Gamma-Carboxylase antibody
Anti-Gamma-Glutamyl Carboxylase antibody
Anti-Peptidyl-Glutamate 4-Carboxylase antibody
Anti-Vitamin K Gamma Glutamyl Carboxylase antibody
Anti-GGCX antibody
Anti-GC antibody

Information sourced from Uniprot.org

Citations

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