Anti-GGCX antibody (400-450) {FITC} (STJ501153)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationFITC
IsotypeIgG
ImmunogenSynthetic peptide taken within amino acid region 400-450 on human GGCX protein.
General Information
| Short Description | Rabbit polyclonal antibody anti-GGCX (400-450) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Applications | ELISA/IHC/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | FITC |
| Concentration | 0.55-0.75 ยตg/ยตl |
| Purification | Affinity Purified |
| Dilution Range | WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:150IHC: 1:50-1:100 |
| Formulation | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction | Store at-20ยฐC for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | GGCX |
| Gene ID | 2677 |
| Uniprot ID | VKGC_HUMAN |
| Immunogen | Synthetic peptide taken within amino acid region 400-450 on human GGCX protein. |
| Immunogen Region | 400-450 |
Additional Info
| Function | Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide. Catalyzes gamma-carboxylation of various proteins, such as blood coagulation factors (F2, F7, F9 and F10), osteocalcin (BGLAP) or matrix Gla protein (MGP). |
| Protein Name | Vitamin K-Dependent Gamma-CarboxylaseGamma-Glutamyl CarboxylasePeptidyl-Glutamate 4-CarboxylaseVitamin K Gamma Glutamyl Carboxylase |
| Database Links | Reactome: R-HSA-159740Reactome: R-HSA-9673240 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Vitamin K-Dependent Gamma-Carboxylase antibodyAnti-Gamma-Glutamyl Carboxylase antibodyAnti-Peptidyl-Glutamate 4-Carboxylase antibodyAnti-Vitamin K Gamma Glutamyl Carboxylase antibodyAnti-GGCX antibodyAnti-GC antibody |
Information sourced from Uniprot.org