Anti-GGA2 antibody (GAT domain) (STJ13101138)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from the GAT domain of mouse GGA2 conjugated to an immunogenic carrier protein was used as the antigen. The antigen is homologous in rat.
General Information
| Short Description | Rabbit polyclonal anti-GGA2 (GAT domain) for use in IHC and WB in Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20ยฐC for long term storage and refrigerated at 2-8ยฐC for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | Gga2 |
| Gene ID | 74105 |
| Uniprot ID | GGA2_MOUSE |
| Immunogen | A synthetic peptide from the GAT domain of mouse GGA2 conjugated to an immunogenic carrier protein was used as the antigen. The antigen is homologous in rat. |
| Immunogen Region | GAT domain |
| Specificity | Specific for GGA2. |
Additional Info
| Function | Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (DXXLL) motif. Mediates export of the GPCR receptor ADRA2B to the cell surface. Regulates retrograde transport of phosphorylated form of BACE1 from endosomes to the trans-Golgi network. |
| Protein Name | Adp-Ribosylation Factor-Binding Protein Gga2Gamma-Adaptin-Related Protein 2Golgi-Localized - Gamma Ear-Containing - Arf-Binding Protein 2 |
| Database Links | |
| Cellular Localisation | Golgi ApparatusTrans-Golgi Network MembranePeripheral Membrane ProteinEndosome MembraneEarly Endosome Membrane |
| Alternative Antibody Names | Anti-Adp-Ribosylation Factor-Binding Protein Gga2 antibodyAnti-Gamma-Adaptin-Related Protein 2 antibodyAnti-Golgi-Localized - Gamma Ear-Containing - Arf-Binding Protein 2 antibodyAnti-Gga2 antibodyAnti-Kiaa1080 antibody |
Information sourced from Uniprot.org