Anti-GFPT1 antibody [R01-2I2] (STJA0034363)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human GFPT1
General Information
| Short Description | Rabbit monoclonal anti-GFPT1 for use in WB, IHC-P and IP in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IP |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R01-2I2 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IP 1:20 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | GFPT1 |
| Gene ID | 2673 |
| Uniprot ID | GFPT1_HUMAN |
| Immunogen | A synthetic peptide of human GFPT1 |
Additional Info
| Tissue Specificity | Isoform 1 is predominantly expressed in skeletal muscle. Not expressed in brain. Seems to be selectively expressed in striated muscle. |
| Function | Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins. Regulates the circadian expression of clock genes BMAL1 and CRY1. Has a role in fine tuning the metabolic fluctuations of cytosolic UDP-GlcNAc and its effects on hyaluronan synthesis that occur during tissue remodeling. |
| Protein Name | Glutamine--Fructose-6-Phosphate Aminotransferase Isomerizing 1D-Fructose-6-Phosphate Amidotransferase 1Glutamine -Fructose-6-Phosphate Amidotransferase 1Gfat 1Gfat1Hexosephosphate Aminotransferase 1 |
| Database Links | Reactome: R-HSA-381038Reactome: R-HSA-4085023Reactome: R-HSA-446210 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Glutamine--Fructose-6-Phosphate Aminotransferase Isomerizing 1 antibodyAnti-D-Fructose-6-Phosphate Amidotransferase 1 antibodyAnti-Glutamine -Fructose-6-Phosphate Amidotransferase 1 antibodyAnti-Gfat 1 antibodyAnti-Gfat1 antibodyAnti-Hexosephosphate Aminotransferase 1 antibodyAnti-GFPT1 antibodyAnti-GFAT antibodyAnti-GFPT antibody |
Information sourced from Uniprot.org