Anti-GFPT1 antibody (1-150) (STJ23774)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal GFPT1 (1-150) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GFPT1 |
| Gene ID | 2673 |
| Uniprot ID | GFPT1_HUMAN |
| Immunogen Region | 1-150 |
| Immunogen Sequence | MCGIFAYLNYHVPRTRREIL ETLIKGLQRLEYRGYDSAGV GFDGGNDKDWEANACKIQLI KKKGKVKALDEEVHKQQDMD LDIEFDVHLGIAHTRWATHG EPSPVNSHPQRSDKNNEFIV IHNGIITNYKDLKKFLESKG YDFESETDTE |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human GFPT1 (NP_002047.2). |
Additional Info
| Tissue Specificity | Isoform 1 is predominantly expressed in skeletal muscle. Not expressed in brain. Seems to be selectively expressed in striated muscle. |
| Function | Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins. Regulates the circadian expression of clock genes BMAL1 and CRY1. Has a role in fine tuning the metabolic fluctuations of cytosolic UDP-GlcNAc and its effects on hyaluronan synthesis that occur during tissue remodeling. |
| Protein Name | Glutamine--Fructose-6-Phosphate Aminotransferase Isomerizing 1D-Fructose-6-Phosphate Amidotransferase 1Glutamine -Fructose-6-Phosphate Amidotransferase 1Gfat 1Gfat1Hexosephosphate Aminotransferase 1 |
| Database Links | Reactome: R-HSA-381038Reactome: R-HSA-4085023Reactome: R-HSA-446210 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Glutamine--Fructose-6-Phosphate Aminotransferase Isomerizing 1 antibodyAnti-D-Fructose-6-Phosphate Amidotransferase 1 antibodyAnti-Glutamine -Fructose-6-Phosphate Amidotransferase 1 antibodyAnti-Gfat 1 antibodyAnti-Gfat1 antibodyAnti-Hexosephosphate Aminotransferase 1 antibodyAnti-GFPT1 antibodyAnti-GFAT antibodyAnti-GFPT antibody |
Information sourced from Uniprot.org