• Immunofluorescence analysis of A549 cells, using GFM2 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of lysates from LOVO and RAW264.7 cells, using GFM2 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Immunohistochemical analysis of paraffin-embedded Human lung cancer. Antibody was diluted at 1:100 (4°C overnight). High-pressure and temperature Tris-EDTA, pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.

Anti-GFM2 antibody (441-490 aa) (STJ92842)

SKU:
STJ92842

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Ribosome-releasing factor 2, mitochondrial (441-490 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GFM2
Gene ID: 84340
Uniprot ID: RRF2M_HUMAN
Immunogen Region: 441-490 aa
Specificity: EF-G2 Polyclonal Antibody detects endogenous levels of EF-G2 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human GFM2 at the amino acid range 441-490
Function Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. Promotes mitochondrial ribosome recycling by dissolution of intersubunit contacts. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
Protein Name Ribosome-Releasing Factor 2 - Mitochondrial
Rrf2mt
Elongation Factor G 2 - Mitochondrial
Ef-G2mt
Mef-G 2
Elongation Factor G2
Hefg2
Database Links Reactome: R-HSA-5419276
Cellular Localisation Mitochondrion
Alternative Antibody Names Anti-Ribosome-Releasing Factor 2 - Mitochondrial antibody
Anti-Rrf2mt antibody
Anti-Elongation Factor G 2 - Mitochondrial antibody
Anti-Ef-G2mt antibody
Anti-Mef-G 2 antibody
Anti-Elongation Factor G2 antibody
Anti-Hefg2 antibody
Anti-GFM2 antibody
Anti-EFG2 antibody
Anti-MSTP027 antibody

Information sourced from Uniprot.org

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