• Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:100
  • Western blot analysis of HBE cells using ALR Polyclonal Antibody.. Secondary antibody was diluted at 1:20000

Anti-GFER antibody (51-100 aa) (STJ96894)

SKU:
STJ96894

Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-FAD-linked sulfhydryl oxidase ALR (51-100 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC-P 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GFER
Gene ID: 2671
Uniprot ID: ALR_HUMAN
Immunogen Region: 51-100 aa
Specificity: ALR Polyclonal Antibody detects endogenous levels of ALR protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human GFER at the amino acid range 51-100
Function Isoform 1: FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecular oxygen. Isoform 2: May act as an autocrine hepatotrophic growth factor promoting liver regeneration.
Protein Name Fad-Linked Sulfhydryl Oxidase Alr
Augmenter Of Liver Regeneration
Herv1
Hepatopoietin
Database Links Reactome: R-HSA-1268020
Cellular Localisation Isoform 1: Mitochondrion Intermembrane Space
Mitochondrion
Isoform 2: Cytoplasm
Secreted
Alternative Antibody Names Anti-Fad-Linked Sulfhydryl Oxidase Alr antibody
Anti-Augmenter Of Liver Regeneration antibody
Anti-Herv1 antibody
Anti-Hepatopoietin antibody
Anti-GFER antibody
Anti-ALR antibody
Anti-HERV1 antibody
Anti-HPO antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance