Anti-GDF2/BMP9 antibody (Internal) (STJ71565)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-GDF2/BMP9 (Internal) is suitable for use in ELISA research applications. |
| Applications | Pep-ELISA |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:4000.WB: Preliminary experiments gave an approx 27kDa band in Human Bone Marrow, Liver, and Brain (cerebellum) lysates after 1µg/ml antibody staining. Please note that currently we cannot find a |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | GDF2 |
| Gene ID | 2658 |
| Uniprot ID | GDF2_HUMAN |
| Accession Number | NP_057288.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | KRWVRSDSTKSK |
Additional Info
| Post Translational Modifications | A reversible disulfide bond can be formed between the two subunits in the homodimer.this has no effect on GDF2 activity. |
| Function | Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG. |
| Protein Name | Growth/Differentiation Factor 2Gdf-2Bone Morphogenetic Protein 9Bmp-9 |
| Database Links | Reactome: R-HSA-201451 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Growth/Differentiation Factor 2 antibodyAnti-Gdf-2 antibodyAnti-Bone Morphogenetic Protein 9 antibodyAnti-Bmp-9 antibodyAnti-GDF2 antibodyAnti-BMP9 antibody |
Information sourced from Uniprot.org