Anti-GDE1/MIR16 antibody (230-242) (STJ73164)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-GDE1/MIR16 (230-242) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx 50kDa band observed in Mouse and Rat Brain lysates (calculated MW of 37.7kDa according to NP_057725.1). The observed molecular weight corresponds to the glycosylated form. Reco |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | GDE1 |
| Gene ID | 51573 |
| Uniprot ID | GDE1_HUMAN |
| Accession Number | NP_057725.1 |
| Immunogen Region | 230-242 |
| Immunogen Sequence | SLSHTGDGKPRYD |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Hydrolyzes the phosphodiester bond of glycerophosphodiesters such as glycerophosphoinositol (GroPIns) and glycerophosphoethanolamine (GroPEth), to yield a glycerol phosphate and an alcohol. Hydrolyzes glycerophospho-N-acylethanolamines to N-acylethanolamines in the brain and participates in bioactive N-acylethanolamine biosynthesis such as anandamide (an endocannabinoid), N-palmitoylethanolamine (an anti-inflammatory), and N-oleoylethanolamine (an anorexic). In addition, has a lysophospholipase D activity by hydrolyzing N-acyl-lysoplasmenylethanolamine (N-acyl-lysoPlsEt) to N-acylethanolamine. However lysophospholipase D activity is lower than glycerophosphodiester phosphodiesterase activity. Has little or no activity towards glycerophosphocholine. |
| Protein Name | Glycerophosphodiester Phosphodiesterase 1Glycerophosphoinositol Glycerophosphodiesterase Gde1Lysophospholipase D Gde1Membrane-Interacting Protein Of Rgs16Rgs16-Interacting Membrane Protein |
| Database Links | Reactome: R-HSA-6814848 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCytoplasmic Vesicle MembranePerinuclear Vesicles And Cell Membrane |
| Alternative Antibody Names | Anti-Glycerophosphodiester Phosphodiesterase 1 antibodyAnti-Glycerophosphoinositol Glycerophosphodiesterase Gde1 antibodyAnti-Lysophospholipase D Gde1 antibodyAnti-Membrane-Interacting Protein Of Rgs16 antibodyAnti-Rgs16-Interacting Membrane Protein antibodyAnti-GDE1 antibodyAnti-MIR16 antibody |
Information sourced from Uniprot.org