Anti-GCLC antibody [R02-8B5] (STJA0036399)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human GCLC
General Information
| Short Description | Rabbit monoclonal anti-GCLC for use in WB in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R02-8B5 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | GCLC |
| Gene ID | 2729 |
| Uniprot ID | GSH1_HUMAN |
| Immunogen | A synthesized peptide derived from human GCLC |
Additional Info
| Function | Catalyzes the ATP-dependent ligation of L-glutamate and L-cysteine and participates in the first and rate-limiting step in glutathione biosynthesis. |
| Protein Name | Glutamate--Cysteine Ligase Catalytic SubunitGcs Heavy ChainGamma-EcsGamma-Glutamylcysteine Synthetase |
| Database Links | Reactome: R-HSA-174403Reactome: R-HSA-5578999Reactome: R-HSA-9818027 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Glutamate--Cysteine Ligase Catalytic Subunit antibodyAnti-Gcs Heavy Chain antibodyAnti-Gamma-Ecs antibodyAnti-Gamma-Glutamylcysteine Synthetase antibodyAnti-GCLC antibodyAnti-GLCL antibodyAnti-GLCLC antibody |
Information sourced from Uniprot.org