Anti-GCC2 antibody (1-300) (STJ115756)

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STJ115756
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Short Description :Rabbit polyclonal GCC2 (1-300) antibody for use in WB, IHC-P and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IHC-P/ELISA
Host:Rabbit
Reactivity:Human/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:Lot specific
Purification:Affinity purification
Dilution Range:WB:1:500-1:2000
IHC-P:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation:PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:GCC2
Gene ID:9648
Uniprot ID:GCC2_HUMAN
Immunogen Region:1-300
Immunogen Sequence:MEDLVQDGVASPATPGTGKS KLETLPKEDLIKFAKKQMML IQKAKSRCTELEKEIEELRS KPVTEGTGDIIKALTERLDA LLLEKAETEQQCLSLKKENI KMKQEVEDSVTKMGDAHKEL EQSHINYVKEIENLKNELMA VRSKYSEDKANLQKQLEEAM NTQLELSEQLKFQNNSEDNV KKLQEEIEKIRPGFEEQILY LQKQLDATTDEKKETVTQLQ NIIEANSQHYQKNINSLQE
Specificity:Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GCC2 (NP_852118.1).
Tissue Specificity Ubiquitous.
Function Golgin which probably tethers transport vesicles to the trans-Golgi network (TGN) and regulates vesicular transport between the endosomes and the Golgi. As a RAB9A effector it is involved in recycling of the mannose 6-phosphate receptor from the late endosomes to the TGN. May also play a role in transport between the recycling endosomes and the Golgi. Required for maintenance of the Golgi structure, it is involved in the biogenesis of noncentrosomal, Golgi-associated microtubules through recruitment of CLASP1 and CLASP2.
Protein Name Grip And Coiled-Coil Domain-Containing Protein 2
185 Kda Golgi Coiled-Coil Protein
Gcc185
Cll-Associated Antigen Kw-11
Ctcl Tumor Antigen Se1-1
Ran-Binding Protein 2-Like 4
Ranbp2l4
Renal Carcinoma Antigen Ny-Ren-53
Database Links Reactome: R-HSA-6811440
Reactome: R-HSA-9725370
Cellular Localisation Cytoplasm
Golgi Apparatus
Trans-Golgi Network Membrane
Peripheral Membrane Protein
Alternative Antibody Names Anti-Grip And Coiled-Coil Domain-Containing Protein 2 antibody
Anti-185 Kda Golgi Coiled-Coil Protein antibody
Anti-Gcc185 antibody
Anti-Cll-Associated Antigen Kw-11 antibody
Anti-Ctcl Tumor Antigen Se1-1 antibody
Anti-Ran-Binding Protein 2-Like 4 antibody
Anti-Ranbp2l4 antibody
Anti-Renal Carcinoma Antigen Ny-Ren-53 antibody
Anti-GCC2 antibody
Anti-KIAA0336 antibody
Anti-RANBP2L4 antibody

Information sourced from Uniprot.org