| Host: |
Rabbit |
| Applications: |
WB/IHC-P/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GCC2 |
| Gene ID: |
9648 |
| Uniprot ID: |
GCC2_HUMAN |
| Immunogen Region: |
1-300 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GCC2 (NP_852118.1). |
| Immunogen Sequence: |
MEDLVQDGVASPATPGTGKS KLETLPKEDLIKFAKKQMML IQKAKSRCTELEKEIEELRS KPVTEGTGDIIKALTERLDA LLLEKAETEQQCLSLKKENI KMKQEVEDSVTKMGDAHKEL EQSHINYVKEIENLKNELMA VRSKYSEDKANLQKQLEEAM NTQLELSEQLKFQNNSEDNV KKLQEEIEKIRPGFEEQILY LQKQLDATTDEKKETVTQLQ NIIEANSQHYQKNINSLQE |
| Tissue Specificity | Ubiquitous. |
| Function | Golgin which probably tethers transport vesicles to the trans-Golgi network (TGN) and regulates vesicular transport between the endosomes and the Golgi. As a RAB9A effector it is involved in recycling of the mannose 6-phosphate receptor from the late endosomes to the TGN. May also play a role in transport between the recycling endosomes and the Golgi. Required for maintenance of the Golgi structure, it is involved in the biogenesis of noncentrosomal, Golgi-associated microtubules through recruitment of CLASP1 and CLASP2. |
| Protein Name | Grip And Coiled-Coil Domain-Containing Protein 2185 Kda Golgi Coiled-Coil ProteinGcc185Cll-Associated Antigen Kw-11Ctcl Tumor Antigen Se1-1Ran-Binding Protein 2-Like 4Ranbp2l4Renal Carcinoma Antigen Ny-Ren-53 |
| Database Links | Reactome: R-HSA-6811440Reactome: R-HSA-9725370 |
| Cellular Localisation | CytoplasmGolgi ApparatusTrans-Golgi Network MembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Grip And Coiled-Coil Domain-Containing Protein 2 antibodyAnti-185 Kda Golgi Coiled-Coil Protein antibodyAnti-Gcc185 antibodyAnti-Cll-Associated Antigen Kw-11 antibodyAnti-Ctcl Tumor Antigen Se1-1 antibodyAnti-Ran-Binding Protein 2-Like 4 antibodyAnti-Ranbp2l4 antibodyAnti-Renal Carcinoma Antigen Ny-Ren-53 antibodyAnti-GCC2 antibodyAnti-KIAA0336 antibodyAnti-RANBP2L4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
