Anti-GCC185 antibody (Internal) (STJ71284)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-GCC185 (Internal) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/IHC |
| Host | Goat |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Preliminary experiments gave an approx 60kDa band in Human Lymph Node and Testis lysates after 0.03µg/ml antibody staining. Please note that currently we cannot find an explanation in |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | GCC2 |
| Gene ID | 9648 |
| Uniprot ID | GCC2_HUMAN |
| Accession Number | NP_055450.1; NP_852118.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | QKLTNKNNKIED |
| Specificity | This antibody is expected to recognise both reported isoforms (NP_055450.1and NP_852118.1). |
Additional Info
| Function | Golgin which probably tethers transport vesicles to the trans-Golgi network (TGN) and regulates vesicular transport between the endosomes and the Golgi. As a RAB9A effector it is involved in recycling of the mannose 6-phosphate receptor from the late endosomes to the TGN. May also play a role in transport between the recycling endosomes and the Golgi. Required for maintenance of the Golgi structure, it is involved in the biogenesis of noncentrosomal, Golgi-associated microtubules through recruitment of CLASP1 and CLASP2. |
| Protein Name | Grip And Coiled-Coil Domain-Containing Protein 2185 Kda Golgi Coiled-Coil ProteinGcc185Cll-Associated Antigen Kw-11Ctcl Tumor Antigen Se1-1Ran-Binding Protein 2-Like 4Ranbp2l4Renal Carcinoma Antigen Ny-Ren-53 |
| Database Links | Reactome: R-HSA-6811440Reactome: R-HSA-9725370 |
| Cellular Localisation | CytoplasmGolgi ApparatusTrans-Golgi Network MembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Grip And Coiled-Coil Domain-Containing Protein 2 antibodyAnti-185 Kda Golgi Coiled-Coil Protein antibodyAnti-Gcc185 antibodyAnti-Cll-Associated Antigen Kw-11 antibodyAnti-Ctcl Tumor Antigen Se1-1 antibodyAnti-Ran-Binding Protein 2-Like 4 antibodyAnti-Ranbp2l4 antibodyAnti-Renal Carcinoma Antigen Ny-Ren-53 antibodyAnti-GCC2 antibodyAnti-KIAA0336 antibodyAnti-RANBP2L4 antibody |
Information sourced from Uniprot.org