| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-GCA (1-217) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:100 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GCA |
| Gene ID: |
25801 |
| Uniprot ID: |
GRAN_HUMAN |
| Immunogen Region: |
1-217 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-217 of human GCA (NP_036330.1). |
| Immunogen Sequence: |
MAYPGYGGGFGNFSIQVPGM QMGQPVPETGPAILLDGYSG PAYSDTYSSAGDSVYTYFSA VAGQDGEVDAEELQRCLTQS GINGTYSPFSLETCRIMIAM LDRDHTGKMGFNAFKELWAA LNAWKENFMTVDQDGSGTVE HHELRQAIGLMGYRLSPQTL TTIVKRYSKNGRIFFDDYVA CCVKLRALTDFFRKRDHLQQ GSANFIYDDFLQGTMAI |
| Tissue Specificity | Detected in neutrophils and macrophages (at protein level). Highly expressed in bone marrow. |
| Function | Calcium-binding protein that may play a role in the adhesion of neutrophils to fibronectin. May play a role in the formation of focal adhesions. |
| Protein Name | Grancalcin |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | CytoplasmCytoplasmic Granule MembranePeripheral Membrane ProteinCytoplasmic SidePrimarily Cytosolic In The Absence Of Calcium Or Magnesium IonsRelocates To Granules And Other Membranes In Response To Elevated Calcium And Magnesium Levels |
| Alternative Antibody Names | Anti-Grancalcin antibodyAnti-GCA antibodyAnti-GCL antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
