• Western blot analysis of lysates from Jarkat cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-GAS2 antibody (STJ190841)

SKU:
STJ190841

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Growth arrest-specific protein 2 is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GAS2
Gene ID: 2620
Uniprot ID: GAS2_HUMAN
Specificity: GAS2 Polyclonal Antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from part of the human protein
Post Translational Modifications Cleaved, during apoptosis, on a specific aspartic residue by caspases. Phosphorylated on serine residues during the G0-G1 transition phase.
Function May play a role in apoptosis by acting as a cell death substrate for caspases. Is cleaved during apoptosis and the cleaved form induces dramatic rearrangements of the actin cytoskeleton and potent changes in the shape of the affected cells. May be involved in the membrane ruffling process.
Protein Name Growth Arrest-Specific Protein 2
Gas-2
Database Links Reactome: R-HSA-264870
Cellular Localisation Cytoplasm
Cytoskeleton
Stress Fiber
Membrane
Peripheral Membrane Protein
Component Of The Microfilament System
Colocalizes With Actin Fibers At The Cell Border And Along The Stress Fibers In Growth-Arrested Fibroblasts
Mainly Membrane-Associated
When Hyperphosphorylated
Accumulates At Membrane Ruffles
Alternative Antibody Names Anti-Growth Arrest-Specific Protein 2 antibody
Anti-Gas-2 antibody
Anti-GAS2 antibody

Information sourced from Uniprot.org

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