Anti-GARS1/Glycyl-tRNA synthetase antibody [SAA1935] (STJA0020363)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
General Information
| Short Description | Mouse monoclonal Glycine--Trna Ligase antibody for use in ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA1935 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Protein A/G purified from cell culture supernatant |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
Target Information
| Gene Symbol | GARS1 |
| Gene ID | 2617 |
| Uniprot ID | GARS_HUMAN |
Additional Info
| Function | Catalyzes the ATP-dependent ligation of glycine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (Gly-AMP). Also produces diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs. Thereby, may play a special role in Ap4A homeostasis. |
| Protein Name | Glycine--Trna LigaseDiadenosine Tetraphosphate SynthetaseAp4a SynthetaseGlycyl-Trna SynthetaseGlyrsGlycyl-Trna Synthetase 1 |
| Database Links | Reactome: R-HSA-379716Reactome: R-HSA-379726 |
| Cellular Localisation | CytoplasmCell ProjectionAxonSecretedExtracellular ExosomeIn Transfected Cos7 CellsNot Detected In MitochondriaNor In Golgi ApparatusSecreted By Motor NeuronPossibly Through The Exosome PathwayIsoform 1: MitochondrionIsoform 2: Cytoplasm |
| Alternative Antibody Names | Anti-Glycine--Trna Ligase antibodyAnti-Diadenosine Tetraphosphate Synthetase antibodyAnti-Ap4a Synthetase antibodyAnti-Glycyl-Trna Synthetase antibodyAnti-Glyrs antibodyAnti-Glycyl-Trna Synthetase 1 antibodyAnti-GARS1 antibodyAnti-GARS antibody |
Information sourced from Uniprot.org