Anti-GAN antibody (400-450) {FITC} (STJ507836)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationFITC
IsotypeIgG
ImmunogenSynthetic peptide corresponding to amino acids within region 400-450 on human DNA-binding protein SATB2 protein.
General Information
| Short Description | Rabbit polyclonal antibody anti-GAN (400-450) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
| Applications | ELISA/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | FITC |
| Purification | Affinity Purified |
| Formulation | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | GAN |
| Gene ID | 8139 |
| Uniprot ID | GAN_HUMAN |
| Immunogen | Synthetic peptide corresponding to amino acids within region 400-450 on human DNA-binding protein SATB2 protein. |
| Immunogen Region | 400-450 |
Additional Info
| Post Translational Modifications | Ubiquitinated by E3 ubiquitin ligase complex formed by CUL3 and RBX1 and probably targeted for proteasome-independent degradation. |
| Function | Probable cytoskeletal component that directly or indirectly plays an important role in neurofilament architecture. May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Controls degradation of TBCB. Controls degradation of MAP1B and MAP1S, and is critical for neuronal maintenance and survival. |
| Protein Name | GigaxoninKelch-Like Protein 16 |
| Database Links | Reactome: R-HSA-8951664Reactome: R-HSA-983168 |
| Cellular Localisation | CytoplasmCytoskeleton |
| Alternative Antibody Names | Anti-Gigaxonin antibodyAnti-Kelch-Like Protein 16 antibodyAnti-GAN antibodyAnti-GAN1 antibodyAnti-KLHL16 antibody |
Information sourced from Uniprot.org