Anti-GALNT2 antibody (442-571) (STJ28990)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal GALNT2 (442-571) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:100-1:500IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GALNT2 |
| Gene ID | 2590 |
| Uniprot ID | GALT2_HUMAN |
| Immunogen Region | 442-571 |
| Immunogen Sequence | HQDIAFGALQQGTNCLDTLG HFADGVVGVYECHNAGGNQE WALTKEKSVKHMDLCLTVVD RAPGSLIKLQGCRENDSRQK WEQIEGNSKLRHVGSNLCLD SRTAKSGGLSVEVCGPALSQ QWKFTLNLQQ |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 442-571 of human GALNT2 (NP_004472.1). |
Additional Info
| Tissue Specificity | Detected in urine (at protein level). Widely expressed. |
| Function | Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b. Probably involved in O-linked glycosylation of the immunoglobulin A1 (IgA1) hinge region. Involved in O-linked glycosylation of APOC-III, ANGPTL3 and PLTP. It participates in the regulation of HDL-C metabolism. |
| Protein Name | Polypeptide N-Acetylgalactosaminyltransferase 2Polypeptide Galnac Transferase 2Galnac-T2Pp-Gantase 2Protein-Udp Acetylgalactosaminyltransferase 2Udp-Galnac -Polypeptide N-Acetylgalactosaminyltransferase 2 Cleaved Into - Polypeptide N-Acetylgalactosaminyltransferase 2 Soluble Form |
| Database Links | Reactome: R-HSA-6811436Reactome: R-HSA-913709 |
| Cellular Localisation | Golgi ApparatusGolgi Stack MembraneSingle-Pass Type Ii Membrane ProteinSecretedResides Preferentially In The Trans And Medial Parts Of The Golgi StackA Secreted Form Also Exists |
| Alternative Antibody Names | Anti-Polypeptide N-Acetylgalactosaminyltransferase 2 antibodyAnti-Polypeptide Galnac Transferase 2 antibodyAnti-Galnac-T2 antibodyAnti-Pp-Gantase 2 antibodyAnti-Protein-Udp Acetylgalactosaminyltransferase 2 antibodyAnti-Udp-Galnac -Polypeptide N-Acetylgalactosaminyltransferase 2 Cleaved Into - Polypeptide N-Acetylgalactosaminyltransferase 2 Soluble Form antibodyAnti-GALNT2 antibody |
Information sourced from Uniprot.org