Anti-GALNT12 antibody (STJA0004582)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenFusion protein of human GALNT12
General Information
| Short Description | Rabbit polyclonal anti-Polypeptide N-Acetylgalactosaminyltransferase 12 for use in IHC and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1.26 mg/mL |
| Purification | Antigen affinity purification |
| Dilution Range | IHC 1:50-1:300 |
| Formulation | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | GALNT12 |
| Gene ID | 79695 |
| Uniprot ID | GLT12_HUMAN |
| Immunogen | Fusion protein of human GALNT12 |
Additional Info
| Tissue Specificity | Widely expressed at different levels of expression. Highly expressed in digestive organs such as small intestine, stomach, pancreas and colon. Expressed at intermediate level in testis, thyroid gland and spleen. Weakly expressed in whole brain, cerebral cortex, cerebellum, fetal brain, bone marrow, thymus, leukocytes, heart, skeletal muscle, liver, lung, esophagus, kidney, adrenal gland, mammary gland, uterus, placenta, ovary and prostate. |
| Function | Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward non-glycosylated peptides such as Muc5AC, Muc1a and EA2, and no detectable activity with Muc2 and Muc7. Displays enzymatic activity toward the Gal-NAc-Muc5AC glycopeptide, but no detectable activity to mono-GalNAc-glycosylated Muc1a, Muc2, Muc7 and EA2. May play an important role in the initial step of mucin-type oligosaccharide biosynthesis in digestive organs. |
| Protein Name | Polypeptide N-Acetylgalactosaminyltransferase 12Polypeptide Galnac Transferase 12Galnac-T12Pp-Gantase 12Protein-Udp Acetylgalactosaminyltransferase 12Udp-Galnac -Polypeptide N-Acetylgalactosaminyltransferase 12 |
| Database Links | Reactome: R-HSA-5083636Reactome: R-HSA-913709 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Polypeptide N-Acetylgalactosaminyltransferase 12 antibodyAnti-Polypeptide Galnac Transferase 12 antibodyAnti-Galnac-T12 antibodyAnti-Pp-Gantase 12 antibodyAnti-Protein-Udp Acetylgalactosaminyltransferase 12 antibodyAnti-Udp-Galnac -Polypeptide N-Acetylgalactosaminyltransferase 12 antibodyAnti-GALNT12 antibody |
Information sourced from Uniprot.org