Anti-GALC antibody (40-300) (STJ111199)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal GALC (40-300) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GALC |
| Gene ID | 2581 |
| Uniprot ID | GALC_HUMAN |
| Immunogen Region | 40-300 |
| Immunogen Sequence | GGAYVLDDSDGLGREFDGIG AVSGGGATSRLLVNYPEPYR SQILDYLFKPNFGASLHILK VEIGGDGQTTDGTEPSHMHY ALDENYFRGYEWWLMKEAKK RNPNITLIGLPWSFPGWLGK GFDWPYVNLQLTAYYVVTWI VGAKRYHDLDIDYIGIWNER SYNANYIKILRKMLNYQGLQ RVKIIASDNLWESISASMLL DAELFKVVDVIGAHYPGTHS AKDAKLTGKKLWSSEDFST |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 40-300 of human GALC (NP_000144.2). |
Additional Info
| Tissue Specificity | Detected in urine. Detected in testis, brain and placenta (at protein level). Detected in kidney and liver. |
| Function | Hydrolyzes the galactose ester bonds of glycolipids such as galactosylceramide and galactosylsphingosine. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon. |
| Protein Name | GalactocerebrosidaseGalceraseGalactocerebroside Beta-GalactosidaseGalactosylceramidaseGalactosylceramide Beta-Galactosidase |
| Database Links | Reactome: R-HSA-9840310 |
| Cellular Localisation | Lysosome |
| Alternative Antibody Names | Anti-Galactocerebrosidase antibodyAnti-Galcerase antibodyAnti-Galactocerebroside Beta-Galactosidase antibodyAnti-Galactosylceramidase antibodyAnti-Galactosylceramide Beta-Galactosidase antibodyAnti-GALC antibody |
Information sourced from Uniprot.org