Anti-GAD65/GAD2 antibody [SRM14565] (STJ11109295)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
General Information
| Short Description | Rabbit monoclonal GAD65/GAD2 antibody for use in WB, IP and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IP/ELISA |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM14565 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity purification |
| Dilution Range | WB, 1:30000-1:100000IP, 0.5 Mu g-4 Mu g antibody for 200 Mu g-600 Mu g extracts of whole cellsELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GAD2 |
| Gene ID | 2572 |
| Uniprot ID | DCE2_HUMAN |
| Immunogen | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
Additional Info
| Post Translational Modifications | Phosphorylated.which does not affect kinetic parameters or subcellular location. Palmitoylated.which is required for presynaptic clustering. |
| Function | Catalyzes the production of GABA. |
| Protein Name | Glutamate Decarboxylase 265 Kda Glutamic Acid DecarboxylaseGad-65Glutamate Decarboxylase 65 Kda Isoform |
| Database Links | Reactome: R-HSA-888568Reactome: R-HSA-888590Reactome: R-HSA-9022927 |
| Cellular Localisation | CytoplasmCytosolCytoplasmic VesiclePresynaptic Cell MembraneLipid-AnchorGolgi Apparatus MembranePeripheral Membrane ProteinCytoplasmic SideAssociated To Cytoplasmic VesiclesIn NeuronsCytosolic Leaflet Of Golgi Membranes And Presynaptic Clusters |
| Alternative Antibody Names | Anti-Glutamate Decarboxylase 2 antibodyAnti-65 Kda Glutamic Acid Decarboxylase antibodyAnti-Gad-65 antibodyAnti-Glutamate Decarboxylase 65 Kda Isoform antibodyAnti-GAD2 antibodyAnti-GAD65 antibody |
Information sourced from Uniprot.org