Anti-GAD65/GAD2 antibody [SMM15061] (STJ11109791)

SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
STJ11109791
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General Information

Short DescriptionMouse monoclonal GAD65/GAD2 antibody for use in WB, IF-P, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IF-P/IHC-P/ELISA
HostMouse
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDSMM15061
IsotypeIgG
ConjugationUnconjugated
PurificationAffinity purification
Dilution RangeWB, 1:2500-1:10000
IF-P, 1:200-1:800
IHC-P, 1:1000-1:4000
ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolGAD2
Gene ID2572
Uniprot IDDCE2_HUMAN
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.

Additional Info

Post Translational Modifications Phosphorylated.which does not affect kinetic parameters or subcellular location. Palmitoylated.which is required for presynaptic clustering.
Function Catalyzes the production of GABA.
Protein Name Glutamate Decarboxylase 2
65 Kda Glutamic Acid Decarboxylase
Gad-65
Glutamate Decarboxylase 65 Kda Isoform
Database Links Reactome: R-HSA-888568
Reactome: R-HSA-888590
Reactome: R-HSA-9022927
Cellular Localisation Cytoplasm
Cytosol
Cytoplasmic Vesicle
Presynaptic Cell Membrane
Lipid-Anchor
Golgi Apparatus Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Associated To Cytoplasmic Vesicles
In Neurons
Cytosolic Leaflet Of Golgi Membranes And Presynaptic Clusters
Alternative Antibody Names Anti-Glutamate Decarboxylase 2 antibody
Anti-65 Kda Glutamic Acid Decarboxylase antibody
Anti-Gad-65 antibody
Anti-Glutamate Decarboxylase 65 Kda Isoform antibody
Anti-GAD2 antibody
Anti-GAD65 antibody

Information sourced from Uniprot.org

Citations

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