Anti-GAD65 antibody [6D5-E8-E4] (STJA0032507)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2b
ImmunogenPurified recombinant human GAD2 protein fragments expressed in E.coli.
General Information
| Short Description | Mouse monoclonal anti-GAD65 for use in WB in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Mouse |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 6D5-E8-E4 |
| Isotype | IgG2b |
| Conjugation | Unconjugated |
| Concentration | 4.76 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | GAD2 |
| Gene ID | 2572 |
| Uniprot ID | DCE2_HUMAN |
| Immunogen | Purified recombinant human GAD2 protein fragments expressed in E.coli. |
Additional Info
| Post Translational Modifications | Phosphorylated.which does not affect kinetic parameters or subcellular location. Palmitoylated.which is required for presynaptic clustering. |
| Function | Catalyzes the production of GABA. |
| Protein Name | Glutamate Decarboxylase 265 Kda Glutamic Acid DecarboxylaseGad-65Glutamate Decarboxylase 65 Kda Isoform |
| Database Links | Reactome: R-HSA-888568Reactome: R-HSA-888590Reactome: R-HSA-9022927 |
| Cellular Localisation | CytoplasmCytosolCytoplasmic VesiclePresynaptic Cell MembraneLipid-AnchorGolgi Apparatus MembranePeripheral Membrane ProteinCytoplasmic SideAssociated To Cytoplasmic VesiclesIn NeuronsCytosolic Leaflet Of Golgi Membranes And Presynaptic Clusters |
| Alternative Antibody Names | Anti-Glutamate Decarboxylase 2 antibodyAnti-65 Kda Glutamic Acid Decarboxylase antibodyAnti-Gad-65 antibodyAnti-Glutamate Decarboxylase 65 Kda Isoform antibodyAnti-GAD2 antibodyAnti-GAD65 antibody |
Information sourced from Uniprot.org