| Short Description : | Goat polyclonal antibody anti-GAD1-Isoform (Internal) is suitable for use in ELISA, Western Blot, Immunofluorescence and Flow Cytometry research applications. |
| Applications: | Pep-ELISA/WB/IF/FC |
| Host: | Goat |
| Reactivity: | Human/Mouse/Rat/Dog/Cow/Pig |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 0.5 mg/mL |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx 70kDa band observed in Human Cerebellum, and in Mouse and Rat Brain lysates (calculated MW of 66.9kDa according to Human NP_000808.2, and 66.6kDa according to Mouse NP_032103.2 |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | GAD1 |
| Gene ID: | 2571 |
| Uniprot ID: | DCE1_HUMAN |
| Accession Number: | NP_000808.2 |
| Immunogen Region: | Internal |
| Immunogen Sequence: | PDSPQRREKLHK |
| Specificity: | This antibody is expected to recognize isoform GAD67. There is no cross-reactivity expected with GAD2. |
| Function | Catalyzes the synthesis of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) with pyridoxal 5'-phosphate as cofactor. Isoform 3: Enzymatically inactive as glutamate decarboxylase. |
| Protein Name | Glutamate Decarboxylase 167 Kda Glutamic Acid DecarboxylaseGad-67Glutamate Decarboxylase 67 Kda Isoform |
| Database Links | Reactome: R-HSA-888568Reactome: R-HSA-888590Reactome: R-HSA-9022927 |
| Alternative Antibody Names | Anti-Glutamate Decarboxylase 1 antibodyAnti-67 Kda Glutamic Acid Decarboxylase antibodyAnti-Gad-67 antibodyAnti-Glutamate Decarboxylase 67 Kda Isoform antibodyAnti-GAD1 antibodyAnti-GAD antibodyAnti-GAD67 antibody |
Information sourced from Uniprot.org
