| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-GABRR1 (365-465) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GABRR1 |
| Gene ID: |
2569 |
| Uniprot ID: |
GBRR1_HUMAN |
| Immunogen Region: |
365-465 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 365-465 of human GABRR1 (NP_002033.2). |
| Immunogen Sequence: |
VNYLTTVQERKEQKLREKLP CTSGLPPPRTAMLDGNYSDG EVNDLDNYMPENGEKPDRMM VQLTLASERSSPQRKSQRSS YVSMRIDTHAIDKYSRIIFP A |
| Tissue Specificity | Highly expressed in the retina and in a lesser extent in brain, lung and thymus. |
| Function | GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor could play a role in retinal neurotransmission. |
| Protein Name | Gamma-Aminobutyric Acid Receptor Subunit Rho-1Gaba(A Receptor Subunit Rho-1Gaba(C Receptor |
| Database Links | Reactome: R-HSA-977443 |
| Cellular Localisation | Postsynaptic Cell MembraneMulti-Pass Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-Gamma-Aminobutyric Acid Receptor Subunit Rho-1 antibodyAnti-Gaba(A Receptor Subunit Rho-1 antibodyAnti-Gaba(C Receptor antibodyAnti-GABRR1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
