• Western blot analysis of extracts of various cell lines, using GABA A Receptor beta 1 (GABRB1) (GABRB1) Rabbit monoclonal antibody (STJ11103081) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-GABA A Receptor beta 1 antibody (350-450) [S1MR] (STJ11103081)

SKU:
STJ11103081

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-GABA A Receptor beta 1 (GABRB1) (350-450) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S1MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GABRB1
Gene ID: 2560
Uniprot ID: GBRB1_HUMAN
Immunogen Region: 350-450
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 350-450 of human GABA A Receptor beta 1 (GABRB1) (NP_000803.2).
Immunogen Sequence: EKNKLEMNKVQVDAHGNILL STLEIRNETSGSEVLTSVSD PKATMYSYDSASIQYRKPLS SREAYGRALDRHGVPSKGRI RRRASQLKVKIPDLTDVNSI D
Function Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital.these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel.
Protein Name Gamma-Aminobutyric Acid Receptor Subunit Beta-1
Gaba(A Receptor Subunit Beta-1
Database Links Reactome: R-HSA-1236394
Reactome: R-HSA-977443
Cellular Localisation Postsynaptic Cell Membrane
Multi-Pass Membrane Protein
Cell Membrane
Alternative Antibody Names Anti-Gamma-Aminobutyric Acid Receptor Subunit Beta-1 antibody
Anti-Gaba(A Receptor Subunit Beta-1 antibody
Anti-GABRB1 antibody

Information sourced from Uniprot.org

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