Anti-GAA antibody [2G7] (STJ16103428)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2b
ImmunogenA synthetic peptide corresponding to a sequence in the middle region of human GAA, different from the related mouse sequence by eight amino acids, and from the related rat sequence by six amino acids.
General Information
| Short Description | Mouse monoclonal anti-GAA for use in FC, IF, IHC, ICC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC/IF/IHC/ICC/WB |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 2G7 |
| Isotype | IgG2b |
| Conjugation | Unconjugated |
| Concentration | Adding 0.2 mL of distilled water =f 500 Mu g/mL. |
| Purification | Lyophilized |
| Formulation | Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. NA |
| Storage Instruction | Store at-20°C for up to 1 year. Minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | GAA |
| Gene ID | 2548 |
| Uniprot ID | LYAG_HUMAN |
| Immunogen | A synthetic peptide corresponding to a sequence in the middle region of human GAA, different from the related mouse sequence by eight amino acids, and from the related rat sequence by six amino acids. |
Additional Info
| Function | Essential for the degradation of glycogen in lysosomes. Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans. |
| Protein Name | Lysosomal Alpha-GlucosidaseAcid MaltaseAglucosidase Alfa Cleaved Into - 76 Kda Lysosomal Alpha-Glucosidase - 70 Kda Lysosomal Alpha-Glucosidase |
| Database Links | Reactome: R-HSA-5357609Reactome: R-HSA-6798695Reactome: R-HSA-70221 |
| Cellular Localisation | LysosomeLysosome Membrane |
| Alternative Antibody Names | Anti-Lysosomal Alpha-Glucosidase antibodyAnti-Acid Maltase antibodyAnti-Aglucosidase Alfa Cleaved Into - 76 Kda Lysosomal Alpha-Glucosidase - 70 Kda Lysosomal Alpha-Glucosidase antibodyAnti-GAA antibody |
Information sourced from Uniprot.org