Anti-G6PC1 antibody (200-300) (STJ11104216)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal Glucose-6-Phosphatase Catalytic Subunit 1 (200-300) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:5000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | G6PC1 |
| Gene ID | 2538 |
| Uniprot ID | G6PC1_HUMAN |
| Immunogen Region | 200-300 |
| Immunogen Sequence | SIYNASLKKYFLITFFLFSF AIGFYLLLKGLGVDLLWTLE KAQRWCEQPEWVHIDTTPFA SLLKNLGTLFGLGLALNSSM YRESCKGKLSKWLPFRLSSI V |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human G6PC (NP_000142.2). |
Additional Info
| Function | Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. Forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production in the terminal step of glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels. |
| Protein Name | Glucose-6-Phosphatase Catalytic Subunit 1Glucose-6-PhosphataseG-6-PaseG6paseGlucose-6-Phosphatase AlphaG6pase-Alpha |
| Database Links | Reactome: R-HSA-3274531Reactome: R-HSA-70263Reactome: R-HSA-9615017 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Glucose-6-Phosphatase Catalytic Subunit 1 antibodyAnti-Glucose-6-Phosphatase antibodyAnti-G-6-Pase antibodyAnti-G6pase antibodyAnti-Glucose-6-Phosphatase Alpha antibodyAnti-G6pase-Alpha antibodyAnti-G6PC1 antibodyAnti-G6PC antibodyAnti-G6PT antibody |
Information sourced from Uniprot.org