Anti-G3BP2 antibody (433-482 aa) (STJ93174)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human G3BP2 at the amino acid range 433-482
General Information
| Short Description | Rabbit polyclonal anti-Ras GTPase-activating protein-binding protein 2 (433-482 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | G3BP2 |
| Gene ID | 9908 |
| Uniprot ID | G3BP2_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human G3BP2 at the amino acid range 433-482 |
| Immunogen Region | 433-482 aa |
| Specificity | G3BP2 Polyclonal Antibody detects endogenous levels of G3BP2 protein. |
Additional Info
| Function | Scaffold protein that plays an essential role in cytoplasmic stress granule formation which acts as a platform for antiviral signaling. Plays an essential role in stress granule formation. Stress granules are membraneless compartments that store mRNAs and proteins, such as stalled translation pre-initiation complexes, in response to stress. Promotes formation of stress granules phase-separated membraneless compartment by undergoing liquid-liquid phase separation (LLPS) upon unfolded RNA-binding: functions as a molecular switch that triggers RNA-dependent LLPS in response to a rise in intracellular free RNA concentrations. |
| Protein Name | Ras Gtpase-Activating Protein-Binding Protein 2G3bp-2Gap Sh3 Domain-Binding Protein 2 |
| Database Links | Reactome: R-HSA-9705671 |
| Cellular Localisation | CytoplasmStress Granule |
| Alternative Antibody Names | Anti-Ras Gtpase-Activating Protein-Binding Protein 2 antibodyAnti-G3bp-2 antibodyAnti-Gap Sh3 Domain-Binding Protein 2 antibodyAnti-G3BP2 antibodyAnti-KIAA0660 antibody |
Information sourced from Uniprot.org