Host: |
Rabbit |
Applications: |
WB/ELISA |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Ras GTPase-activating protein-binding protein 2 (433-482 aa) is suitable for use in Western Blot and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000ELISA 1:10000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
G3BP2 |
Gene ID: |
9908 |
Uniprot ID: |
G3BP2_HUMAN |
Immunogen Region: |
433-482 aa |
Specificity: |
G3BP2 Polyclonal Antibody detects endogenous levels of G3BP2 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human G3BP2 at the amino acid range 433-482 |
Function | Scaffold protein that plays an essential role in cytoplasmic stress granule formation which acts as a platform for antiviral signaling. Plays an essential role in stress granule formation. Stress granules are membraneless compartments that store mRNAs and proteins, such as stalled translation pre-initiation complexes, in response to stress. Promotes formation of stress granules phase-separated membraneless compartment by undergoing liquid-liquid phase separation (LLPS) upon unfolded RNA-binding: functions as a molecular switch that triggers RNA-dependent LLPS in response to a rise in intracellular free RNA concentrations. |
Protein Name | Ras Gtpase-Activating Protein-Binding Protein 2G3bp-2Gap Sh3 Domain-Binding Protein 2 |
Database Links | Reactome: R-HSA-9705671 |
Cellular Localisation | CytoplasmStress Granule |
Alternative Antibody Names | Anti-Ras Gtpase-Activating Protein-Binding Protein 2 antibodyAnti-G3bp-2 antibodyAnti-Gap Sh3 Domain-Binding Protein 2 antibodyAnti-G3BP2 antibodyAnti-KIAA0660 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance