Anti-G2E3 antibody (196-246) (STJA0006686)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human G2E3 AA range: 196-246
General Information
| Short Description | Rabbit polyclonal anti-G2/M phase-specific E3 ubiquitin-protein ligase (196-246) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | G2E3 |
| Gene ID | 55632 |
| Uniprot ID | G2E3_HUMAN |
| Immunogen | Synthesized peptide derived from human G2E3 AA range: 196-246 |
| Immunogen Region | 196-246 |
| Specificity | This antibody detects endogenous levels of human G2E3 |
Additional Info
| Function | E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Essential in early embryonic development to prevent apoptotic death. |
| Protein Name | G2/M Phase-Specific E3 Ubiquitin-Protein LigaseG2/M Phase-Specific Hect-Type E3 Ubiquitin Transferase |
| Database Links | |
| Cellular Localisation | NucleusNucleolusCytoplasmShuttles Between The Nucleus And The CytoplasmIn The NucleusDelocalizes From The Nucleolus To The Nucleoplasm In Response To Dna Damage |
| Alternative Antibody Names | Anti-G2/M Phase-Specific E3 Ubiquitin-Protein Ligase antibodyAnti-G2/M Phase-Specific Hect-Type E3 Ubiquitin Transferase antibodyAnti-G2E3 antibodyAnti-KIAA1333 antibody |
Information sourced from Uniprot.org