• Western blot analysis using Fyb monoclonal antibody against Jurkat, K562, TF-1 cell lysate.

Anti-FYB1 antibody (STJ98493)

SKU:
STJ98493

Current Stock:
Host: Mouse
Applications: WB
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-FYN-binding protein 1 is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Conjugation: Unconjugated
Formulation: Liquid in 0.1M Tris-Glycine (pH7.4, 150 mM NaCl) , 0.2% Sodium Azide and 50% Glycerol.
Purification: Affinity purification
Concentration: 1 mg/mL
Dilution Range: WB 1:1000-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FYB1
Gene ID: 2533
Uniprot ID: FYB1_HUMAN
Specificity: Fyb Monoclonal Antibody detects endogenous levels of Fyb protein.
Immunogen: Purified recombinant human Fyb protein fragments expressed in E.coli.
Post Translational Modifications T-cell receptor ligation leads to increased tyrosine phosphorylation.
Function Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells. May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton. Modulates the expression of IL2. Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2. May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells.
Protein Name Fyn-Binding Protein 1
Adhesion And Degranulation Promoting Adaptor Protein
Adap
Fyb-120/130
P120/P130
Fyn-T-Binding Protein
Slap-130
Slp-76-Associated Phosphoprotein
Database Links Reactome: R-HSA-202433
Reactome: R-HSA-391160
Cellular Localisation Cytoplasm
Nucleus
Cell Junction
Colocalizes With Tmem47 At Cell-Cell Contacts In Podocytes
Alternative Antibody Names Anti-Fyn-Binding Protein 1 antibody
Anti-Adhesion And Degranulation Promoting Adaptor Protein antibody
Anti-Adap antibody
Anti-Fyb-120/130 antibody
Anti-P120/P130 antibody
Anti-Fyn-T-Binding Protein antibody
Anti-Slap-130 antibody
Anti-Slp-76-Associated Phosphoprotein antibody
Anti-FYB1 antibody
Anti-FYB antibody
Anti-SLAP130 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance