Anti-FXYD5/dysadherin antibody [SAA1878] (STJA0020306)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
General Information
| Short Description | Mouse monoclonal Fxyd Domain-Containing Ion Transport Regulator 5 antibody for use in ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA1878 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Protein A/G purified from cell culture supernatant |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
Target Information
| Gene Symbol | FXYD5 |
| Gene ID | 53827 |
| Uniprot ID | FXYD5_HUMAN |
Additional Info
| Function | Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. May increase NKA activity by increasing the apparent affinity for Na(+). Involved in down-regulation of E-cadherin which results in reduced cell adhesion. Promotes metastasis. |
| Protein Name | Fxyd Domain-Containing Ion Transport Regulator 5Dysadherin |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinBasolateral Cell MembraneIn Kidneys Localizes To The Basolateral Membrane Of The Connecting Tubule |
| Alternative Antibody Names | Anti-Fxyd Domain-Containing Ion Transport Regulator 5 antibodyAnti-Dysadherin antibodyAnti-FXYD5 antibodyAnti-DYSAD antibodyAnti-IWU1 antibodyAnti-HSPC113 antibodyAnti-UNQ2561 antibodyAnti-PRO6241 antibody |
Information sourced from Uniprot.org