Anti-FUT8 antibody (376-575) (STJ114799)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal FUT8 (376-575) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FUT8 |
| Gene ID | 2530 |
| Uniprot ID | FUT8_HUMAN |
| Immunogen Region | 376-575 |
| Immunogen Sequence | FHPIEEYMVHVEEHFQLLAR RMQVDKKRVYLATDDPSLLK EAKTKYPNYEFISDNSISWS AGLHNRYTENSLRGVILDIH FLSQADFLVCTFSSQVCRVA YEIMQTLHPDASANFHSLDD IYYFGGQNAHNQIAIYAHQP RTADEIPMEPGDIIGVAGNH WDGYSKGVNRKLGRTGLYPS YKVREKIETVKYPTYPEAEK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 376-575 of human FUT8 (NP_835367.1). |
Additional Info
| Post Translational Modifications | Tyrosine phosphorylated by PKDCC/VLK. |
| Function | Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. |
| Protein Name | Alpha-(1 -6-FucosyltransferaseAlpha1-6fuctFucosyltransferase 8Gdp-L-Fuc -N-Acetyl-Beta-D-Glucosaminide Alpha1 -6-FucosyltransferaseGdp-Fucose--Glycoprotein FucosyltransferaseGlycoprotein 6-Alpha-L-Fucosyltransferase |
| Database Links | Reactome: R-HSA-9694548Reactome: R-HSA-975578 |
| Cellular Localisation | Golgi ApparatusGolgi Stack MembraneSingle-Pass Type Ii Membrane ProteinMembrane-Bound Form In Trans Cisternae Of Golgi |
| Alternative Antibody Names | Anti-Alpha-(1 -6-Fucosyltransferase antibodyAnti-Alpha1-6fuct antibodyAnti-Fucosyltransferase 8 antibodyAnti-Gdp-L-Fuc -N-Acetyl-Beta-D-Glucosaminide Alpha1 -6-Fucosyltransferase antibodyAnti-Gdp-Fucose--Glycoprotein Fucosyltransferase antibodyAnti-Glycoprotein 6-Alpha-L-Fucosyltransferase antibodyAnti-FUT8 antibody |
Information sourced from Uniprot.org