• Immunofluorescence analysis of PC-2 cells using CD15 monoclonal antibody (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
  • Anti-FUT4 antibody [4E10] (STJ97906)
  • Immunohistochemistry analysis of paraffin-embedded human cerebellum tissues (left) and human liver cancer tissues (right) with DAB staining using CD15 monoclonal antibody.

Anti-FUT4 antibody [4E10] (STJ97906)

SKU:
STJ97906

€173.75 - €420.00
Current Stock:
Host: Mouse
Applications: IHC/IF/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Alpha-1, 3-fucosyltransferase 4 is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Monoclonal
Clone ID: 4E10
Conjugation: Unconjugated
Isotype: IgG1
Formulation: Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol.
Purification: Affinity purification
Dilution Range: IHC 1:200-1:1000
IF 1:200-1:1000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FUT4
Gene ID: 2526
Uniprot ID: FUT4_HUMAN
Specificity: CD15 Monoclonal Antibody detects endogenous levels of CD15 protein.
Immunogen: Synthesized peptide of human CD15.
Function Isoform Short: Catalyzes alpha(1->3) linkage of fucosyl moiety transferred from GDP-beta-L-fucose to N-acetyl glucosamine (GlcNAc) within type 2 lactosamine (LacNAc, Gal-beta(1->4)GlcNAc) glycan attached to N- or O-linked glycoproteins. Robustly fucosylates nonsialylated distal LacNAc unit of the polylactosamine chain to form Lewis X antigen (CD15), a glycan determinant known to mediate important cellular functions in development and immunity. Fucosylates with lower efficiency sialylated LacNAc acceptors to form sialyl Lewis X and 6-sulfo sialyl Lewis X determinants that serve as recognition epitopes for C-type lectins. Together with FUT7 contributes to SELE, SELL and SELP selectin ligand biosynthesis and selectin-dependent lymphocyte homing, leukocyte migration and blood leukocyte homeostasis. In a cell type specific manner, may also fucosylate the internal LacNAc unit of the polylactosamine chain to form VIM-2 antigen that serves as recognition epitope for SELE. Isoform Long: Does not generate Lewis X antigens.
Protein Name Alpha-(1 -3-Fucosyltransferase 4
4-Galactosyl-N-Acetylglucosaminide 3-Alpha-L-Fucosyltransferase
Elam-1 Ligand Fucosyltransferase
Fucosyltransferase 4
Fucosyltransferase Iv
Fuc-Tiv
Fuct-Iv
Galactoside 3-L-Fucosyltransferase
Database Links Reactome: R-HSA-9037629
Cellular Localisation Golgi Apparatus
Golgi Stack Membrane
Single-Pass Type Ii Membrane Protein
Membrane-Bound Form In Trans Cisternae Of Golgi
Alternative Antibody Names Anti-Alpha-(1 -3-Fucosyltransferase 4 antibody
Anti-4-Galactosyl-N-Acetylglucosaminide 3-Alpha-L-Fucosyltransferase antibody
Anti-Elam-1 Ligand Fucosyltransferase antibody
Anti-Fucosyltransferase 4 antibody
Anti-Fucosyltransferase Iv antibody
Anti-Fuc-Tiv antibody
Anti-Fuct-Iv antibody
Anti-Galactoside 3-L-Fucosyltransferase antibody
Anti-FUT4 antibody
Anti-ELFT antibody
Anti-FCT3A antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance