| Host: |
Goat |
| Applications: |
Pep-ELISA/WB/IHC |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-FUT2 (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
WB-1-3µg/mlIHC-5µg/mlELISA-antibody detection limit dilution 1:64000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
FUT2 |
| Gene ID: |
2524 |
| Uniprot ID: |
FUT2_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_000502.4 |
| Specificity: |
Reported variants represent identical protein: NP_001091107.1, NP_000502.4 |
| Immunogen Sequence: |
HVQQRLAKIQAMWE |
| Function | Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the terminal galactose on both O- and N-linked glycans chains of cell surface glycoproteins and glycolipids and the resulting epitope regulates several processes such as cell-cell interaction including host-microbe interaction, cell surface expression and cell proliferation. Preferentially fucosylates gangliosides GA1 and GM1 in the antrum, cecum and colon and in the female reproductive organs. Fucosylated host glycoproteins or glycolipids mediate interaction with intestinal microbiota influencing its composition. Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble ABO blood group antigen synthesis pathway. |
| Protein Name | Galactoside Alpha-(1 -2-Fucosyltransferase 2Alpha(1 -2ft 2Fucosyltransferase 2Gdp-L-Fucose -Beta-D-Galactoside 2-Alpha-L-Fucosyltransferase 2Se2Secretor Blood Group Alpha-2-FucosyltransferaseSecretor FactorSeType 1 Galactoside Alpha-(1 -2-Fucosyltransferase Fut2Type 2 Galactoside Alpha-(1 -2-Fucosyltransferase Fut2 |
| Database Links | Reactome: R-HSA-9033807Reactome: R-HSA-9037629 |
| Cellular Localisation | Golgi ApparatusGolgi Stack MembraneSingle-Pass Type Ii Membrane ProteinMembrane-Bound Form In Trans Cisternae Of Golgi |
| Alternative Antibody Names | Anti-Galactoside Alpha-(1 -2-Fucosyltransferase 2 antibodyAnti-Alpha(1 -2ft 2 antibodyAnti-Fucosyltransferase 2 antibodyAnti-Gdp-L-Fucose -Beta-D-Galactoside 2-Alpha-L-Fucosyltransferase 2 antibodyAnti-Se2 antibodyAnti-Secretor Blood Group Alpha-2-Fucosyltransferase antibodyAnti-Secretor Factor antibodyAnti-Se antibodyAnti-Type 1 Galactoside Alpha-(1 -2-Fucosyltransferase Fut2 antibodyAnti-Type 2 Galactoside Alpha-(1 -2-Fucosyltransferase Fut2 antibodyAnti-FUT2 antibodyAnti-SEC2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
