Anti-FUT11 antibody (25-205) (STJ11103969)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal Alpha (1-3-Fucosyltransferase 11 (25-205) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20Β°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FUT11 |
| Gene ID | 170384 |
| Uniprot ID | OFUT4_HUMAN |
| Immunogen Region | 25-205 |
| Immunogen Sequence | GSVAEREAGGEAEWAEPWDG AVFRPPSALGAVGVTRSSGT PRPGREEAGDLPVLLWWSPG LFPHFPGDSERIECARGACV ASRNRRALRDSRTRALLFYG TDFRASAAPLPRLAHQSWAL LHEESPLNNFLLSHGPGIRL FNLTSTFSRHSDYPLSLQWL PGTAYLRRPVPPPMERAEWR R |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 25-205 of human FUT11 (NP_775811.2). |
Additional Info
| Function | Protein O-fucosyltransferase that specifically catalyzes O-fucosylation of serine or threonine residues in EMI domains of target proteins, such as MMRN1, MMRN2 and EMID1. Attaches fucose through an O-glycosidic linkage. O-fucosylation of EMI domain-containing proteins may be required for facilitating protein folding and secretion. Also shows minor alpha-(1,3)-fucosyltransferase activity toward activity toward biantennary N-glycan acceptors. However, this was tested with a library of synthetic substrates and this activity is unsure in vivo. |
| Protein Name | Gdp-Fucose Protein O-Fucosyltransferase 4Alpha-(1 -3-Fucosyltransferase 11Fucosyltransferase XiFuc-TxiFuct-XiGalactoside 3-L-Fucosyltransferase 11Fucosyltransferase 11 |
| Database Links | Reactome: R-HSA-9037629 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Gdp-Fucose Protein O-Fucosyltransferase 4 antibodyAnti-Alpha-(1 -3-Fucosyltransferase 11 antibodyAnti-Fucosyltransferase Xi antibodyAnti-Fuc-Txi antibodyAnti-Fuct-Xi antibodyAnti-Galactoside 3-L-Fucosyltransferase 11 antibodyAnti-Fucosyltransferase 11 antibodyAnti-FUT11 antibodyAnti-POFUT4 antibody |
Information sourced from Uniprot.org