Anti-FUNDC2 antibody (STJA0004736)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenFusion protein of human FUNDC2
General Information
| Short Description | Rabbit polyclonal anti-Fun14 Domain-Containing Protein 2 for use in IHC and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1.02 mg/mL |
| Purification | Antigen affinity purification |
| Dilution Range | IHC 1:50-1:300 |
| Formulation | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | FUNDC2 |
| Gene ID | 65991 |
| Uniprot ID | FUND2_HUMAN |
| Immunogen | Fusion protein of human FUNDC2 |
Additional Info
| Tissue Specificity | Highly expressed in platelets (at protein level). |
| Function | Binds directly and specifically 1,2-Diacyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-bisphosphate) (PIP3) leading to the recruitment of PIP3 to mitochondria and may play a role in the regulation of the platelet activation via AKT/GSK3B/cGMP signaling pathways. May act as transcription factor that regulates SREBP1 (isoform SREBP-1C) expression in order to modulate triglyceride (TG) homeostasis in hepatocytes. |
| Protein Name | Fun14 Domain-Containing Protein 2Cervical Cancer Proto-Oncogene 3 ProteinHcc-3Hepatitis C Virus Core-Binding Protein 6 |
| Database Links | |
| Cellular Localisation | Mitochondrion Outer MembraneMulti-Pass Membrane ProteinNucleus |
| Alternative Antibody Names | Anti-Fun14 Domain-Containing Protein 2 antibodyAnti-Cervical Cancer Proto-Oncogene 3 Protein antibodyAnti-Hcc-3 antibodyAnti-Hepatitis C Virus Core-Binding Protein 6 antibodyAnti-FUNDC2 antibodyAnti-HCBP6 antibodyAnti-DC44 antibodyAnti-HCC3 antibodyAnti-PD03104 antibody |
Information sourced from Uniprot.org