• Western blot analysis of AD293 cells using FUNDC1 Polyclonal Antibody diluted at 1：500. Secondary antibody was diluted at 1:20000
  • Western blot analysis of AD293 cells using FUNDC1 Polyclonal Antibody. Antibody was diluted at 1:500. Secondary antibody was diluted at 1:20000

Anti-FUNDC1 antibody (1-50 aa) (STJ97353)

SKU:
STJ97353

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-FUN14 domain-containing protein 1 (1-50 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IF 1:100-300
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FUNDC1
Gene ID: 139341
Uniprot ID: FUND1_HUMAN
Immunogen Region: 1-50 aa
Specificity: FUNDC1 Polyclonal Antibody detects endogenous levels of FUNDC1 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the N-terminal region of human FUNDC1 at the amino acid range 1-50
Post Translational Modifications Phosphorylation at Tyr-18 by SRC inhibits activation of mitophagy. Following hypoxia, dephosphorylated at Tyr-18, leading to interaction with MAP1 LC3 family proteins and triggering mitophagy.
Function Acts as an activator of hypoxia-induced mitophagy, an important mechanism for mitochondrial quality control.
Protein Name Fun14 Domain-Containing Protein 1
Database Links Reactome: R-HSA-8934903
Cellular Localisation Mitochondrion Outer Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Fun14 Domain-Containing Protein 1 antibody
Anti-FUNDC1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance