Anti-FSTL3 antibody [SAA1538] (STJA0019966)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
General Information
| Short Description | Mouse monoclonal Follistatin-Related Protein 3 antibody for use in ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA1538 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Protein A/G purified from cell culture supernatant |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
Target Information
| Gene Symbol | FSTL3 |
| Gene ID | 10272 |
| Uniprot ID | FSTL3_HUMAN |
Additional Info
| Function | Isoform 1 or the secreted form is a binding and antagonizing protein for members of the TGF-beta family, such as activin, BMP2 and MSTN. Inhibits activin A-, activin B-, BMP2- and MSDT-induced cellular signaling.more effective on activin A than on activin B. Involved in bone formation.inhibits osteoclast differentiation. Involved in hematopoiesis.involved in differentiation of hemopoietic progenitor cells, increases hematopoietic cell adhesion to fibronectin and seems to contribute to the adhesion of hematopoietic precursor cells to the bone marrow stroma. Isoform 2 or the nuclear form is probably involved in transcriptional regulation via interaction with MLLT10. |
| Protein Name | Follistatin-Related Protein 3Follistatin-Like Protein 3Follistatin-Related Gene Protein |
| Database Links | Reactome: R-HSA-2473224Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | Isoform 1: SecretedIsoform 2: NucleusAlthough Alternative Initiation Has Been Demonstrated And Resulted In Different LocalizationThe Major Source Of Nuclear Fstl3 Appears Not To Depend On Translation Initiation At Met-27 According To |
| Alternative Antibody Names | Anti-Follistatin-Related Protein 3 antibodyAnti-Follistatin-Like Protein 3 antibodyAnti-Follistatin-Related Gene Protein antibodyAnti-FSTL3 antibodyAnti-FLRG antibodyAnti-UNQ674 antibodyAnti-PRO1308 antibody |
Information sourced from Uniprot.org