| Short Description : | Rabbit polyclonal anti-Follicle-stimulating hormone receptor (211-260 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | IHC-P 100-300WB 1:500-1:2000ELISA 1:5000IF 1:50-200 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FSHR |
| Gene ID: | 2492 |
| Uniprot ID: | FSHR_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human FSHR at the amino acid range 211-260 |
| Immunogen Region: | 211-260 aa |
| Specificity: | FSHR Polyclonal Antibody detects endogenous levels of FSHR protein. |
| Post Translational Modifications | Sulfated. N-glycosylated.indirectly required for FSH-binding, possibly via a conformational change that allows high affinity binding of hormone. |
| Function | G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. |
| Protein Name | Follicle-Stimulating Hormone ReceptorFsh-RFollitropin Receptor |
| Database Links | Reactome: R-HSA-375281Reactome: R-HSA-418555 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Follicle-Stimulating Hormone Receptor antibodyAnti-Fsh-R antibodyAnti-Follitropin Receptor antibodyAnti-FSHR antibodyAnti-LGR1 antibody |
Information sourced from Uniprot.org
