Anti-FSH beta antibody [5E7-6E5-5E7] (STJA0033485)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgA
ImmunogenSynthesized peptide derived from human Follicle-Stimulating Hormone (FSH)
General Information
| Short Description | Mouse monoclonal anti-FSH beta for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 5E7-6E5-5E7 |
| Isotype | IgA |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Dilution Range | IHC 1:100-1:500 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | FSHB |
| Gene ID | 2488 |
| Uniprot ID | FSHB_HUMAN |
| Immunogen | Synthesized peptide derived from human Follicle-Stimulating Hormone (FSH) |
Additional Info
| Function | Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. |
| Protein Name | Follitropin Subunit BetaFollicle-Stimulating Hormone Beta SubunitFsh-BFsh-BetaFollitropin Beta Chain |
| Database Links | Reactome: R-HSA-209822Reactome: R-HSA-375281Reactome: R-HSA-418555 |
| Cellular Localisation | SecretedEfficient Secretion Requires Dimerization With Cga |
| Alternative Antibody Names | Anti-Follitropin Subunit Beta antibodyAnti-Follicle-Stimulating Hormone Beta Subunit antibodyAnti-Fsh-B antibodyAnti-Fsh-Beta antibodyAnti-Follitropin Beta Chain antibodyAnti-FSHB antibody |
Information sourced from Uniprot.org