Anti-FRMPD2 antibody (1161-1211 aa) (STJ195287)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human FRPD2 at the amino acid range 1161-1211
General Information
| Short Description | Rabbit polyclonal anti-FERM and PDZ domain-containing protein 2 (1161-1211 aa) for use in WB in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FRMPD2 |
| Gene ID | 143162 |
| Uniprot ID | FRPD2_HUMAN |
| Immunogen | Synthesized peptide derived from the human FRPD2 at the amino acid range 1161-1211 |
| Immunogen Region | 1161-1211 aa |
| Specificity | This antibody detects endogenous levels of FRPD2 at Human |
Additional Info
| Function | Functions as a scaffold protein and likely plays a role in N-methyl-D-aspartic acid receptor (NMDAR)-mediated synaptic excitatory transmission. May be involved in synapse formation in cone photoreceptor cells. May play a role in the regulation of tight junction formation. Binds phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2). May play a role in the regulation of NOD2-mediated NF-kappa-B activation in immune response. |
| Protein Name | Ferm And Pdz Domain-Containing Protein 2Pdz Domain-Containing Protein 4Pdz Domain-Containing Protein 5c |
| Database Links | |
| Cellular Localisation | CytoplasmBasolateral Cell MembraneCell JunctionTight JunctionPostsynaptic DensityColocalizes With Ctnnb1Cdh1 And Pkp4 At The Basolateral MembraneColocalizes With Tjp1 At Tight JunctionsIts Recruitment To Cell-Cell Contacts Requires Cdh1Colocalizes With Nod2 To The Basolacteral Membrane In Intestinal Epithelial Cells |
| Alternative Antibody Names | Anti-Ferm And Pdz Domain-Containing Protein 2 antibodyAnti-Pdz Domain-Containing Protein 4 antibodyAnti-Pdz Domain-Containing Protein 5c antibodyAnti-FRMPD2 antibodyAnti-PDZD5C antibodyAnti-PDZK4 antibodyAnti-PDZK5C antibody |
Information sourced from Uniprot.org