Function | Functions as a scaffold protein and likely plays a role in N-methyl-D-aspartic acid receptor (NMDAR)-mediated synaptic excitatory transmission. May be involved in synapse formation in cone photoreceptor cells. May play a role in the regulation of tight junction formation. Binds phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2). May play a role in the regulation of NOD2-mediated NF-kappa-B activation in immune response. |
Protein Name | Ferm And Pdz Domain-Containing Protein 2Pdz Domain-Containing Protein 4Pdz Domain-Containing Protein 5c |
Cellular Localisation | CytoplasmBasolateral Cell MembraneCell JunctionTight JunctionPostsynaptic DensityColocalizes With Ctnnb1Cdh1 And Pkp4 At The Basolateral MembraneColocalizes With Tjp1 At Tight JunctionsIts Recruitment To Cell-Cell Contacts Requires Cdh1Colocalizes With Nod2 To The Basolacteral Membrane In Intestinal Epithelial Cells |
Alternative Antibody Names | Anti-Ferm And Pdz Domain-Containing Protein 2 antibodyAnti-Pdz Domain-Containing Protein 4 antibodyAnti-Pdz Domain-Containing Protein 5c antibodyAnti-FRMPD2 antibodyAnti-PDZD5C antibodyAnti-PDZK4 antibodyAnti-PDZK5C antibody |
Information sourced from Uniprot.org