Anti-FRG1 antibody (Internal) (STJ72196)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-FRG1 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:2000.WB: Approx 35kDa double band observed in nuclear lysates of cell line Jurkat (calculated MW of 29.2kDa according to NP_004468.1). This molecular weight is routinely observed by other source |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20ยฐC on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | FRG1 |
| Gene ID | 2483 |
| Uniprot ID | FRG1_HUMAN |
| Accession Number | NP_004468.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | TVTNFGEISGT |
Additional Info
| Function | Binds to mRNA in a sequence-independent manner. May play a role in regulation of pre-mRNA splicing or in the assembly of rRNA into ribosomal subunits. May be involved in mRNA transport. May be involved in epigenetic regulation of muscle differentiation through regulation of activity of the histone-lysine N-methyltransferase KMT5B. |
| Protein Name | Protein Frg1Fshd Region Gene 1 Protein |
| Cellular Localisation | NucleusCajal BodyNucleolusCytoplasmMyofibrilSarcomereZ LineLocalization Changes During Myogenesis From Mainly Cytoplasmic In Undifferentiated MyoblastsTo Strongly Nucleolar In Early Myotubes And Back To Cytoplasmic 5 Days Post-DifferentiationLocalized At The Z-Line In The Sarcomere Of Matured Myotubes 8 Days Post-Differentiation |
| Alternative Antibody Names | Anti-Protein Frg1 antibodyAnti-Fshd Region Gene 1 Protein antibodyAnti-FRG1 antibody |
Information sourced from Uniprot.org