Anti-FRAT1 antibody [R09-6H1] (STJA0034332)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human FRAT1
General Information
| Short Description | Rabbit monoclonal anti-FRAT1 for use in WB, ICC, IF and IP in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ICC/IF/IP |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R09-6H1 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IF 1:50-1:200IP 1:20 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | FRAT1 |
| Gene ID | 10023 |
| Uniprot ID | FRAT1_HUMAN |
| Immunogen | A synthetic peptide of human FRAT1 |
Additional Info
| Post Translational Modifications | Phosphorylated. |
| Function | Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. May play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis. |
| Protein Name | Proto-Oncogene Frat1Frequently Rearranged In Advanced T-Cell Lymphomas 1Frat-1 |
| Database Links | Reactome: R-HSA-196299Reactome: R-HSA-4641262 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Proto-Oncogene Frat1 antibodyAnti-Frequently Rearranged In Advanced T-Cell Lymphomas 1 antibodyAnti-Frat-1 antibodyAnti-FRAT1 antibody |
Information sourced from Uniprot.org