Anti-FPR1 antibody (150-200) (STJ501082)

Name: Anti-FPR1 antibody (150-200) (STJ501082)
SKU: STJ501082-100
Price: 400.5 GBP
Availability: InStock

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SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

ImmunogenSynthetic peptide taken within amino acid region 150-200 on N-formyl peptide receptor.

STJ501082-100

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Short Description	Rabbit polyclonal antibody anti-FPR1 (150-200) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Applications	ELISA/IHC/IP/WB
Host	Rabbit
Reactivity	Human/Monkey/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	0.5 µg/µl
Purification	Affinity Purified
Dilution Range	WB: 1:500 ELISA: 1:10, 000 IP: 1:200 IHC: 1:100
Formulation	Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide).
Storage Instruction	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol	FPR1
Gene ID	2357
Uniprot ID	FPR1_HUMAN
Immunogen	Synthetic peptide taken within amino acid region 150-200 on N-formyl peptide receptor.
Immunogen Region	150-200

Tissue Specificity	Neutrophils.
Post Translational Modifications	Phosphorylated.which is necessary for desensitization.
Function	High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors. Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Receptor for TAFA4, mediates its effects on chemoattracting macrophages, promoting phagocytosis and increasing ROS release. Receptor for cathepsin CTSG, leading to increased phagocyte chemotaxis.
Protein Name	Fmet-Leu-Phe Receptor Fmlp Receptor N-Formyl Peptide Receptor Fpr N-Formylpeptide Chemoattractant Receptor
Database Links	Reactome: R-HSA-418594 Reactome: R-HSA-444473 Reactome: R-HSA-6783783 Reactome: R-HSA-6798695
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein Internalizes In Presence Of Its Ligands Fmlp Tafa4 And Ctsg
Alternative Antibody Names	Anti-Fmet-Leu-Phe Receptor antibody Anti-Fmlp Receptor antibody Anti-N-Formyl Peptide Receptor antibody Anti-Fpr antibody Anti-N-Formylpeptide Chemoattractant Receptor antibody Anti-FPR1 antibody

Information sourced from Uniprot.org