Anti-FOXP2 antibody (C-Term) (STJ70076)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-FOXP2 (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog/Pig/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx 80-90kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 82.6kDa according to NP_683696.2). This molecular weight is routinely observed by other sources. Re |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | FOXP2 |
| Gene ID | 93986 |
| Uniprot ID | FOXP2_HUMAN |
| Accession Number | NP_055306.1; NP_683696.2; NP_683697.1 |
| Immunogen Region | C-Term |
| Immunogen Sequence | REIEEEPLSEDLE |
| Specificity | This antibody is expected to recognise all three reported isoforms (NP_055306.1; NP_683696.2; NP_683697.1). |
Additional Info
| Function | Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels. Involved in neural mechanisms mediating the development of speech and language. |
| Protein Name | Forkhead Box Protein P2Cag Repeat Protein 44Trinucleotide Repeat-Containing Gene 10 Protein |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Forkhead Box Protein P2 antibodyAnti-Cag Repeat Protein 44 antibodyAnti-Trinucleotide Repeat-Containing Gene 10 Protein antibodyAnti-FOXP2 antibodyAnti-CAGH44 antibodyAnti-TNRC10 antibody |
Information sourced from Uniprot.org