| Short Description : | Goat polyclonal antibody anti-FOXI3/Forkhead box I3 (Internal) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Applications: | Pep-ELISA/IHC |
| Host: | Goat |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 0.5 mg/mL |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:4000.IHC: In paraffin embedded Human Bronchus shows strong nuclear staining in the basal cells of the resporatory epithelium. Recommended concentration: 5-10µg/ml. |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | FOXI3 |
| Gene ID: | 344167 |
| Uniprot ID: | FOXI3_HUMAN |
| Accession Number: | NP_001129121.1 |
| Immunogen Region: | Internal |
| Immunogen Sequence: | SPTSISEASADTLQ |
| Function | Transcription factor required for pharyngeal arch development, which is involved in hair, ear, jaw and dental development. May act as a pioneer transcription factor during pharyngeal arch development. Required for epithelial cell differentiation within the epidermis. Acts at multiple stages of otic placode induction: necessary for preplacodal ectoderm to execute an inner ear program. Required for hair follicle stem cell specification. Acts downstream of TBX1 for the formation of the thymus and parathyroid glands from the third pharyngeal pouch. |
| Protein Name | Forkhead Box Protein I3 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Forkhead Box Protein I3 antibodyAnti-FOXI3 antibody |
Information sourced from Uniprot.org
