Anti-FOXI1/FKHL10 antibody (C-Term) (STJ70390)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-FOXI1/FKHL10 (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/WB/IHC |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:8000.WB: Approx 30kDa band observed in Human Testis lysates and in preliminary testing of Human Breast lysate, and approx. 40kDa in preliminary testing of U251 and MCF7 cell lysate l (calculated |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | FOXI1 |
| Gene ID | 2299 |
| Uniprot ID | FOXI1_HUMAN |
| Accession Number | NP_036320.2; NP_658982.1 |
| Immunogen Region | C-Term |
| Immunogen Sequence | TSGVLYPREGTEV |
| Specificity | This antibody is expected to recognise both reported human isoforms (NP_036320.2; NP_658982.1). |
Additional Info
| Function | Transcriptional activator required for the development of normal hearing, sense of balance and kidney function. Required for the expression of SLC26A4/PDS, JAG1 and COCH in a subset of epithelial cells and the development of the endolymphatic system in the inner ear. Also required for the expression of SLC4A1/AE1, SLC4A9/AE4, ATP6V1B1 and the differentiation of intercalated cells in the epithelium of distal renal tubules. |
| Protein Name | Forkhead Box Protein I1Forkhead-Related Protein Fkhl10Forkhead-Related Transcription Factor 6Freac-6Hepatocyte Nuclear Factor 3 Forkhead Homolog 3Hfh-3Hnf-3/Fork-Head Homolog 3 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Forkhead Box Protein I1 antibodyAnti-Forkhead-Related Protein Fkhl10 antibodyAnti-Forkhead-Related Transcription Factor 6 antibodyAnti-Freac-6 antibodyAnti-Hepatocyte Nuclear Factor 3 Forkhead Homolog 3 antibodyAnti-Hfh-3 antibodyAnti-Hnf-3/Fork-Head Homolog 3 antibodyAnti-FOXI1 antibodyAnti-FKHL10 antibodyAnti-FREAC6 antibody |
Information sourced from Uniprot.org